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30 November, 2018 06:59:06 PM / LAST MODIFIED: 2 December, 2018 05:38:40 PM
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China stops work on gene-edited babies

Independent Online Desk
China stops work on gene-edited babies
He Jiankui, who claims to have created the world’s first genetically edited babies, defended his work at a conference in Hong Kong on Wednesday.CreditCreditAnthony Wallace/Agence France-Presse — Getty Images

China said on Thursday (November 29) that it had suspended the work of a scientist who claims to have created the world’s first genetically edited babies, saying his conduct appeared to be unethical and in violation of Chinese law.

The scientist, He Jiankui, announced on Monday that he had used the gene-editing technique Crispr to alter embryos, which he implanted in the womb of a woman who gave birth to twin girls this month. At an international conference on Wednesday, he asserted that he was proud of what he had done.

Xu Nanping, China’s vice minister of science and technology, said Dr. He’s work was still being investigated. But based on news reports, he said, Dr. He appeared to have “blatantly violated China’s relevant laws and regulations” and broken “the bottom line of morality and ethics that the academic community adheres to,” the state broadcaster China Central Television reported on Thursday.

“It is shocking and unacceptable,” Mr. Xu was quoted as saying. “We are resolutely opposed to it.”

The suspension follows international condemnation from scientists who maintain that Dr. He’s conduct was unethical. They say there are serious unanswered questions about the safety of embryo editing and a need to make sure that such research is conducted in a transparent, monitored way so the technology is not misused.

Mr. Xu had said earlier that Chinese regulations issued in 2003 permitted gene-editing experiments on embryos for research purposes, but only if they remained viable for no more than 14 days.

On Monday, a group of 122 Chinese scientists issued a statement calling Dr. He’s actions “crazy” and his claims “a huge blow to the global reputation and development of Chinese science.”

At the Second International Summit on Human Genome Editing in Hong Kong on Wednesday, Dr. He acknowledged that he had not made his university in China aware of the research he was doing. He said he had initially paid for the research himself, then later from his university funding.

Dr. He pushed back against suggestions that he had been secretive about his work, saying that he had presented preliminary aspects of it at conferences and consulted with scientists in the United States and elsewhere. He said he had submitted his research to a scientific journal for review and had not expected to be presenting it at the conference.\

One of many areas of confusion about Dr. He’s research was the status of a possible pregnancy of a second woman he said he had implanted with an edited embryo. On Wednesday, under questioning from scientists after his talk, Dr. He said there had been a second implantation in an early stage.

When asked by Robin Lovell-Badge, a professor of genetics and embryology at the Francis Crick Institute in London, whether by early-stage Dr. He meant a “chemical pregnancy” or early miscarriage, Dr. He said “yes.”

On Thursday, however, Dr. Lovell-Badge told reporters that he could not be sure that Dr. He understood that “chemical pregnancy” referred to a pregnancy that was lost.

“He doesn’t necessarily know what he’s talking about,” Dr. Lovell-Badge said. “We don’t know. He said he confirmed that essentially they’d done the hormone test for whether or not the woman was pregnant. And the answer is yes. But it’s very early, so it could turn into a chemical pregnancy meaning there was a miscarriage. Many embryos fail to survive.”

Dr. He had been scheduled to speak again at the conference on Thursday, but his talk was cancelled.

Dr. Robin Lovell-Badge, who moderated the Wednesday session, said in an email that “it would have been difficult to have sufficient security” for a second talk. He said that Dr. He had decided not to attend after he was told about the security arrangements.

Dr Lovell-Badge said Thursday that the organizers had felt it was “important to give Dr. He a platform to present what he had done.”

“We, therefore, do not regret at all allowing him to present yesterday, but giving him a second opportunity today might also have been viewed as support for him,” he said. “This is another reason the committee did not want him back today.” The New York Times 

BK/SI

 

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Published by the Editor on behalf of Independent Publications Limited at Media Printers, 446/H, Tejgaon I/A, Dhaka-1215.
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Editor : M. Shamsur Rahman
Published by the Editor on behalf of Independent Publications Limited at Media Printers, 446/H, Tejgaon I/A, Dhaka-1215.
Editorial, News & Commercial Offices : Beximco Media Complex, 149-150 Tejgaon I/A, Dhaka-1208, Bangladesh. GPO Box No. 934, Dhaka-1000.

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