Wednesday 21 November 2018 ,
Wednesday 21 November 2018 ,
Latest News
  • Bangladesh excludes Hindu Rohingya families from repatriation: Myanmar
  • 4 killed in Chicago hospital shooting
  • Int'l support must for Bangladesh to ensure inclusive edu for Rohingyas: Unesco
  • 3 killed in Cox’s Bazar ‘gunfight
10 September, 2018 00:00 00 AM
TOXIC METAL & HEART HEALTH

Exposure to arsenic, lead, copper and cadmium linked to increased risk of heart disease

MedicalXpress
Exposure to arsenic, lead, copper and cadmium linked to increased risk of heart disease

Exposure to arsenic, lead, copper and cadmium is associated with an increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published by The BMJ today.

In recent years, exposure to environmental toxic metals such as arsenic, lead, copper, and mercury have become a major global health concern.

Arsenic and cadmium, for example, are known carcinogens, but there are increasing suggestions that exposure to toxic metals may be an independent risk factor for cardiovascular disease.

To investigate further, an international research team, led by Rajiv Chowdhury at the University of Cambridge, reviewed and analysed the results of epidemiological studies that had looked at the association of arsenic, lead, copper, cadmium, and mercury with coronary heart disease, stroke and composite cardiovascular disease.

They identified 37 separate studies published before December 2017 involving almost 350,000 participants. A total of 13,033 coronary heart disease, 4,205 stroke and 15,274 cardiovascular outcomes were reported across the studies.

The studies were designed differently, and were of varying quality, but the researchers were able to allow for that in their analysis.

Exposure to arsenic was found to be significantly associated with a 23% greater relative risk of coronary heart disease and a 30% greater relative risk of composite cardiovascular disease, but there was no evidence of an association with risk of stroke.

Exposure to cadmium and copper was also associated with increased relative risks of coronary heart disease and cardiovascular disease, while lead and cadmium were associated with an increased relative risk of stroke (63% and 72% respectively).

In contrast, mercury was not found to be associated with cardiovascular risk.

The researchers point out that their review was solely based on observational data, which might be affected by unmeasured factors, making it difficult to draw firm conclusions about cause and effect.

Nevertheless, they say their findings "reinforce the (often under-recognised) importance of environmental toxic metals in enhancing globalcardiovascular risk, beyond the roles of conventional behavioural risk factors, such as smoking, poor diet and inactivity."

Furthermore, they say their study highlights the potential need for additional worldwide efforts and strategies "to reduce human exposures even in settings where there is a relatively lower average level of exposure (such as many Western countries)."

And they call for further detailed work "to better characterise these associations and to assess causality."

In a linked editorial, Maria Tellez-Plaza at the Carlos III Health Institute in Madrid, and colleagues, agree that metals are an important but neglected source of cardiovascular risk.

This review is "an important call for attention to an emerging group of risk factors with a high prevalence in populations around the world," they say.

Since metals are associated with cardiovascular disease even at relatively low levels of exposure, "population wide strategies to minimize exposure will further contribute to overall cardiovascular prevention efforts," they conclude.

Courtesy: British Medical Journal

 

Comments

Most Viewed
Digital Edition
More story
From the Editor

From the Editor

World Lung Cancer Day has been observed this year with the theme ‘Honour, Unite, Inspire’. Lung cancer continues to be one of the most common…
What is lung cancer?

What is lung cancer?

Lung cancer originates from tissues of the lung, usually from cells lining the air passages. The two main types are small cell lung cancer (SCLC) and…
Understanding lung cancer - the basics

Understanding lung cancer - the basics

Although lung cancer is the leading cause of cancer death in the U.S. in both men and women, it is also one of the most preventable kinds of cancer. At…
Changing paradigm in management of lung cancer

Changing paradigm in management of lung cancer

Lung cancer in Asia is a major public health problem as it contributes to high morbidity and mortality. The incidence of smoking continues to rise in…
The lifestyle changes you can make today to reduce your lung cancer risk

The lifestyle changes you can make today to reduce your lung cancer risk

You already know that lung cancer can develop in someone who's never smoked a cigarette and that the disease is linked to lifestyle risk factors,…
Perimenopause: symptoms, signs and treatment

Perimenopause: symptoms, signs and treatment

Claire Chamberlain   Struggling with irregular periods, extreme bleeding, vaginal dryness, loss of libido or migraine headaches? All of these symptoms…
Your heart hates air pollution portable filters could help

Your heart hates air pollution portable filters could help

Haley Otman Microscopic particles floating in the air we breathe come from sources such as fossil fuel combustion, fires, cigarettes and vehicles. Known…
A complicated case of incomplete therapeutic abortion managed by homeopathy

A complicated case of incomplete therapeutic abortion managed by homeopathy

Patients undergoing induced abortions in hospitals and clinics at times die of profuse haemorrhage. Incidentally I had the opportunity to treat such a…
Acupuncture treatment for infertility & improving ART (IVF) success rate

Acupuncture treatment for infertility & improving ART (IVF) success rate

Infertility means that a couple is not sterile but for some reason has not been able to conceive a child despite of frequent unprotected sex for at least…
Fat-clogged cells explain why obesity can cause cancer

Fat-clogged cells explain why obesity can cause cancer

A new discovery could explain why obese people are more likely to develop cancer, scientists say. A type of cell the body uses to destroy cancerous tissue…
World Diabetes Day Celebration: 150 rallies organised across the country

World Diabetes Day Celebration: 150 rallies organised across the country

World Diabetes Day was observed in the country to raise awareness and promote early diagnosis to prevent this non-communicable disease. To mark the day,…
AstraZeneca's diabetes drug curbs heart failure, kidney risks

AstraZeneca's diabetes drug curbs heart failure, kidney risks

Ben Hirschler The biggest clinical trial so far to assess a new class of diabetes pills shows that AstraZeneca's Farxiga can prevent heart failure…
FDA approves Lorbrena (lorlatinib) for previously-treated ALK-positive metastatic non-small cell lung cancer

FDA approves Lorbrena (lorlatinib) for previously-treated ALK-positive metastatic non-small cell lung cancer

Recently, announced that the U.S. Food and Drug Administration (FDA) has approved Lorbrena [lor-BREN-ah] (lorlatinib), a third-generation anaplastic lymphoma…

Copyright © All right reserved.

Editor : M. Shamsur Rahman

Published by the Editor on behalf of Independent Publications Limited at Media Printers, 446/H, Tejgaon I/A, Dhaka-1215.
Editorial, News & Commercial Offices : Beximco Media Complex, 149-150 Tejgaon I/A, Dhaka-1208, Bangladesh. GPO Box No. 934, Dhaka-1000.

Editor : M. Shamsur Rahman
Published by the Editor on behalf of Independent Publications Limited at Media Printers, 446/H, Tejgaon I/A, Dhaka-1215.
Editorial, News & Commercial Offices : Beximco Media Complex, 149-150 Tejgaon I/A, Dhaka-1208, Bangladesh. GPO Box No. 934, Dhaka-1000.

Disclaimer & Privacy Policy
....................................................
About Us
....................................................
Contact Us
....................................................
Advertisement
....................................................
Subscription

Powered by : Frog Hosting